Which engine type is more efficient, twin-turbo or naturally aspirated?

I'm considering purchasing an Audi R8 but I'm not sure which engine type is more efficient. Can someone explain the difference between twin-turbo and naturally aspirated engines and which one would be better in terms of performance and fuel economy?

The twin-turbo engine in the Audi R8 offers better acceleration and power, making it the ideal choice for performance enthusiasts. However, if fuel economy is your top priority, the naturally aspirated engine may be a better option. It provides smoother power delivery and better fuel efficiency.